Assessment of inflamation and cervical length in treatening miscarriage

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Jan Tuzel, Joanna Niepsuj‑Biniaś, Tomasz Olejniczak, Krzysztof Szymanowski, Tomasz Opala

4 (41) 2014 s. 273–276
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Fraza do cytowania: Tuzel J., Niepsuj‑Biniaś J., Olejniczak T., Szymanowski K., Opala T. Assessment of inflamation and cervical length in treatening miscarriage. Polski Przegląd Nauk o Zdrowiu. 2014;4(41):273–276.

Introduction. The miscarriage is one of the most common pregnancy complication; almost 15% of the confirmed pregnancies is miscarried spontaneously. Although, the etiopathogenesis of miscarriages remains still unexplained completely, many factors leading to miscarriage have been identified. One of them is the infection followed by the inflammation. The reduction of the cervix length seems to correlate positively with the threatened abortion as well. Aim. The aim of the study was to compare inflammatory parameters and cervical length between patients with threatened abortion (treated or untreated) and healthy controls. Material and methods. The study group consisted of 52 women, before 22th gestational week, who were admitted to the Gynecological and Obstetrics Clinical University Hospital in Poznań in 2011–2014 years because of the threatened abortion. Group I comprised patients before the treatment. Group II consisted of the patients during the treatment; group III included healthy controls. Blood samples were analised in the central laboratory of the hospital; The cervical length was measured during gynecological examination as well as the vaginal smears were taken. In the statistical analysis we used the Kruskal‑Wallis test and the ANOVA test; the level of statistical significance was adopted p value < 0.05. Results. The differences between compared three groups in the aspect of gestational age, C-reactive peptide, leukocytes, vaginal biocenosis and the presence of the urine bacteria were not significant. However, the reduction of cervical length in group II in comparison to group III was statistically significant (p = 0,03). Conclusions. The number of patients in the study should be increased and some other biochemical markers should be considered to find out the predictor or distinctive factors in terms of the threatened abortion. The cervical length seems to be one of the factors.

Key words: hypothermia, hypoxic‑ischemic encephalopathy, newborn.



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